BDBM733703 2-((2-((4-(((3-(1-(2-fluoroacryloyl)piperidin-3-yl)phenyl)amino)methyl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)-N-methylbenzamide ::US20250127800, Example 33

SMILES C=C(F)C(=O)N1CCCC(c2cccc(NCc3ccc(Nc4ncc(C(F)(F)F)c(Nc5ccccc5C(=O)NC)n4)cc3)c2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 733703   

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733703(2-((2-((4-(((3-(1-(2-fluoroacryloyl)piperidin-3-yl...)
Affinity DataIC50: 5.11nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent