BDBM733986 US20250127913, Compound I-88

SMILES COc1ccccc1CN1c2cc(-c3cnc(N4CCN(C(=O)COCCOCCOCCOCCOCCOCCn5cc(CC[C@H](NC(=O)c6ccc(NCc7cnc8nc(N)nc(O)c8n7)cc6)C(=O)O)nn5)[C@H](C)C4)nc3)ccc2C(=O)C1(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 733986   

TargetFolate receptor beta(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM733986(US20250127913, Compound I-88)
Affinity DataIC50: 6.90nMAssay Description:Table 15: Folate receptor binding was measured in black 96-well plates using a fluorescence polarization assay. A fluorescent probe consisting of a f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM733986(US20250127913, Compound I-88)
Affinity DataIC50: 60nMAssay Description:Table 15: TNFα binding was measured in black 96-well plates using a time-resolved FRET assay using a previously described fluorescence acceptor TNFα ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent