BDBM734327 US20250129041, Compound AST-DT-218

SMILES COc1ccc([C@@H](C)Nc2cccc3c2CN(C2CCC(=O)NC2=O)C3)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 734327   

TargetProtein cereblon(Human)
Astrogen

US Patent
LigandPNGBDBM734327(US20250129041, Compound AST-DT-218)
Affinity DataKd:  16nMAssay Description:CRBN affinity experiments were performed to evaluate the binding affinity of AST-DT-135, AST-DT-218, and AST-DT-220 to CRBN proteins. First, CRBN pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent