BDBM734434 US20250129067, Compound Anlotinib

SMILES COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ccnc2cc1OCC1(N)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 734434   

TargetVascular endothelial growth factor receptor 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM734434(US20250129067, Compound Anlotinib)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human VEGFR2 using Poly (Glu,Tyr) 4:1 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM734434(US20250129067, Compound Anlotinib)
Affinity DataIC50: 1nMAssay Description:Inhibition of VEGFR-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM734434(US20250129067, Compound Anlotinib)
Affinity DataIC50: 1nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM734434(US20250129067, Compound Anlotinib)
Affinity DataIC50: 115nMAssay Description:Inhibition of recombinant human PDGFRbeta using Poly (Glu,Tyr) 4:1 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Progentos Therapeutics

US Patent
LigandPNGBDBM734434(US20250129067, Compound Anlotinib)
Affinity DataIC50: 1.36E+3nMAssay Description:The PDGFRα enzyme assays were conducted per the manufacturer's directions (Promega PDGFRα Kinase Enzyme System and ADP Glo Assay Cat #V8011). Bri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent