BDBM7350 6-(4-Fluorophenyl)[5H]pyrrolo[2,3-b]pyrazine::6-(4-fluorophenyl)-5H-pyrrolo[2,3-b]pyrazine::6-phenyl[5H]pyrrolo[2,3-b]pyrazine (aloisine) 18

SMILES Fc1ccc(cc1)-c1cc2nccnc2[nH]1

InChI Key InChIKey=OGRORAFGBNLUSP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7350   

TargetGlycogen synthase kinase-3 beta(Rat)
Faculte De Medecine Et De Pharmacie

LigandPNGBDBM7350(6-(4-Fluorophenyl)[5H]pyrrolo[2,3-b]pyrazine | 6-(...)
Affinity DataIC50:  1.90E+3nMT: 30°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
Faculte De Medecine Et De Pharmacie

LigandPNGBDBM7350(6-(4-Fluorophenyl)[5H]pyrrolo[2,3-b]pyrazine | 6-(...)
Affinity DataIC50:  1.00E+3nMT: 30°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Faculte De Medecine Et De Pharmacie

LigandPNGBDBM7350(6-(4-Fluorophenyl)[5H]pyrrolo[2,3-b]pyrazine | 6-(...)
Affinity DataIC50:  2.30E+3nMpH: 7.2 T: 30°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed