BDBM735607 US20250129103, Compound 194
SMILES N#CC[C@H]1CN(c2nc(OCC34CCCN3CCC4)nc3c2CCN(c2cccc4cccc(Cl)c24)C3)CCN1C(=O)/C=C/CN1CC2(COC2)C1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 735607
TargetRAF Proto-oncogen Serine/Threonine-Protein Kinase/GTPase KRas [1-169,G12C,C51S,C80L,C118S](Human)
Frontier Medicines
US Patent
Frontier Medicines
US Patent
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50S for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
