BDBM736418 Synthesis of 5-((1S,3R,4S)-5-fluoro-7-hydroxy-3-(isopentylamino)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-6-yl)-1,2,5-thiadiazolidin-3-one 1,1-dioxide and 5-((1R,3R,4R)-5-fluoro-7-hydroxy-3-(isopentylamino)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-6-yl)-1,2,5-thiadiazolidin-3-one 1,1-dioxide::US20250134882, Example 2

SMILES CC(C)CCN[C@@H]1C[C@@H]2C[C@H]1c1c2cc(O)c(N2CC(=O)NS2(=O)=O)c1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 736418   

TargetReceptor-type tyrosine-protein phosphatase N2 [1-387](Homo sapiens (Human))
Nerio Therapeutics

US Patent
LigandPNGBDBM736418(Synthesis of 5-((1S,3R,4S)-5-fluoro-7-hydroxy-3-(i...)
Affinity DataIC50: 129nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent