BDBM736726 N-[2-amino-5-(4-fluorophenyl)phenyl]-5-(N-cyclopropyl-S-methyl-sulfonimidoyl)benzothiophene-2-carboxamide ::US20250136570, Compound 211

SMILES CS(=O)(=NC1CC1)c1ccc2sc(C(=O)Nc3cc(-c4ccc(F)cc4)ccc3N)cc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 736726   

TargetHistone deacetylase 1(Human)
Tango Therapeutics

US Patent
LigandPNGBDBM736726(N-[2-amino-5-(4-fluorophenyl)phenyl]-5-(N-cyclopro...)
Affinity DataIC50: 100nMAssay Description:IC50 determination for HDAC1 and HDAC3—Prior to adding reagents, 50 nL/well of compound were added to Proxiplates using an Echo dispenser instrument ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Tango Therapeutics

US Patent
LigandPNGBDBM736726(N-[2-amino-5-(4-fluorophenyl)phenyl]-5-(N-cyclopro...)
Affinity DataIC50: 1.25E+3nMAssay Description:IC50 determination for HDAC1 and HDAC3—Prior to adding reagents, 50 nL/well of compound were added to Proxiplates using an Echo dispenser instrument ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent