BDBM7368 4-{7-methyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenyl N,N-dimethylsulfamate::6-(4-Dimethylsulfamoyloxyphenyl)-7-methyl-5H-pyrrolo[2,3-b]pyrazine::6-phenyl[5H]pyrrolo[2,3-b]pyrazine (aloisine) 31

SMILES CN(C)S(=O)(=O)Oc1ccc(cc1)-c1[nH]c2nccnc2c1C

InChI Key InChIKey=HVIKNWLSYBPGOG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7368   

TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
Faculte De Medecine Et De Pharmacie

LigandPNGBDBM7368(4-{7-methyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenyl N...)
Affinity DataIC50:  900nMT: 30°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM7368(4-{7-methyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenyl N...)
Affinity DataIC50:  501nMAssay Description:Inhibitory concentration against Glycogen synthase kinase-3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Faculte De Medecine Et De Pharmacie

LigandPNGBDBM7368(4-{7-methyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenyl N...)
Affinity DataIC50:  700nMT: 30°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Rat)
Faculte De Medecine Et De Pharmacie

LigandPNGBDBM7368(4-{7-methyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenyl N...)
Affinity DataIC50:  500nMT: 30°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed