BDBM736999 1-(4-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,2,3-triazol-5-yl)methoxy)pyridazin-3-yl)piperazin-1-yl)ethan-1-one ::US20250136581, Example 171

SMILES CC(=O)N1CCN(c2ccc(OCc3c(C)nnn3-c3ccc(C(F)F)cc3)nn2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 736999   

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736999(1-(4-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H...)
Affinity DataKi:  1.07nMAssay Description:The affinity of the compound to each subtype of GABAA receptor was determined by competing for the binding of 3H-flunitrazepam to HEK293 cells stably...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent