BDBM737443 US20250136608, Compound 8

SMILES CC(C)(C(CC#N)n1cc(-c2ncnc3[nH]ccc23)cn1)C(F)(F)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 737443   

TargetTyrosine-protein kinase JAK2(Human)
Cgenetech (Suzhou, China) Co.

US Patent
LigandPNGBDBM737443(US20250136608, Compound 8)
Affinity DataIC50: 15nMAssay Description:1) Treatment wells of the compound to be tested (T-compound): In HTRF 96 well low volume plate, 4 μL of 2.5×the compound to be tested described above...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Cgenetech (Suzhou, China) Co.

US Patent
LigandPNGBDBM737443(US20250136608, Compound 8)
Affinity DataIC50: 419nMAssay Description:1) Treatment wells of the compound to be tested (T-compound): In HTRF 96 well low volume plate, 4 μL of 2.5×the compound to be tested described above...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent