BDBM737461 US20250136619, Compound I-18

SMILES CN(C/C=C/C(=O)N1CCC[C@@H](n2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)C1)CCCN1CCN(CCCNS(=O)(=O)c2ccc(Cc3ncc(Br)c(Cc4cccc(F)c4C(N)=O)n3)cc2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 737461   

TargetTyrosine-protein kinase BTK(Human)
Halda Therapeutics OPCO

US Patent
LigandPNGBDBM737461(US20250136619, Compound I-18)
Affinity DataKd: <50nMAssay Description:Compounds were tested using a KdELECT assay. Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 1(Human)
Halda Therapeutics OPCO

US Patent
LigandPNGBDBM737461(US20250136619, Compound I-18)
Affinity DataKd: <50nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1×binding buffer (20% SeaBlock, 0.17×PBS, 0.05%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent