BDBM737465 US20250136619, Compound I-29

SMILES Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCN1CCN(CCCN(C)C/C=C/C(=O)N3CCC[C@@H](n4nc(-c5ccc(Oc6ccccc6)cc5)c5c(N)ncnc54)C3)CC1)c1nnc(C)n1-2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 737465   

TargetBromodomain-containing protein 4 [342-460](Human)
Halda Therapeutics OPCO

US Patent
LigandPNGBDBM737465(US20250136619, Compound I-29)
Affinity DataKd: <50nMAssay Description:Binding reactions were assembled by combining bromodomains, liganded affinity beads, and test compounds in 1×binding buffer (17% SeaBlock, 0.33×PBS, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Halda Therapeutics OPCO

US Patent
LigandPNGBDBM737465(US20250136619, Compound I-29)
Affinity DataKd: <50nMAssay Description:Compounds were tested using a KdELECT assay. Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetBromodomain-containing protein 4 [42-168](Human)
Halda Therapeutics OPCO

US Patent
LigandPNGBDBM737465(US20250136619, Compound I-29)
Affinity DataKd: <50nMAssay Description:Binding reactions were assembled by combining bromodomains, liganded affinity beads, and test compounds in 1×binding buffer (17% SeaBlock, 0.33×PBS, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent