BDBM737486 US20250136619, Compound I-81

SMILES CCc1cnn2c(NCc3ccc(OCCCN4CCN(CCCN(C)C/C=C/C(=O)N(C)CCOc5c(N)ncnc5-c5cc(F)cc(CC(=O)c6ccc(C7CC7)cc6F)c5C)CC4)nc3)cc(N3CCCC[C@H]3CCO)nc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 737486   

TargetTyrosine-protein kinase BTK(Human)
Halda Therapeutics OPCO

US Patent
LigandPNGBDBM737486(US20250136619, Compound I-81)
Affinity DataKd: <50nMAssay Description:Compounds were tested using a KdELECT assay. Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Halda Therapeutics OPCO

US Patent
LigandPNGBDBM737486(US20250136619, Compound I-81)
Affinity DataKd: <50nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1×binding buffer (20% SeaBlock, 0.17×PBS, 0.05%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent