BDBM737518 Synthesis 1-((3R,5R,8S,10S,13S,14S,17S)-3-hydroxy-3,10,13-trimethyl-2,3,4,5,6,7,8,10,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-(2H-1,2,3-triazol-2-yl)ethan-1-one (A23) & 1-((3R,5R,8S,10S,13S,14S,17S)-3-hydroxy-3,10,13-trimethyl-2,3,4,5,6,7,8,10,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-(1H-1,2,3-triazol-1-yl)ethan-1-one (A22)::US20250136638, Example 12

SMILES C[C@@]1(O)CC[C@]2(C)C3=CC[C@]4(C)[C@@H](C(=O)Cn5ccnn5)CC[C@H]4[C@@H]3CC[C@@H]2C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 737518   

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandPNGBDBM737518(Synthesis 1-((3R,5R,8S,10S,13S,14S,17S)-3-hydroxy-...)
Affinity DataIC50: 550nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
9/3/2025
Entry Details
US Patent