BDBM737985 7-(2-((2-chloro-4-(4-(oxetan-3- ylmethyl)piperazin-1- yl)phenyl)amino)-5- (trifluoromethyl)pyrimidin-4-yl)-4- methyl-3,4-dihydrothieno[2,3- f][1,4]thiazepin-5(2H)-one 1,1- dioxide::US20250144094, Example 217

SMILES CN1CCS(=O)(=O)c2cc(-c3nc(Nc4ccc(N5CCN(CC6COC6)CC5)cc4Cl)ncc3C(F)(F)F)sc2C1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 737985   

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM737985(7-(2-((2-chloro-4-(4-(oxetan-3- ylmethyl)piperazin...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent