BDBM738014 7-(2-((7-chloro-2- (cyclopropylmethyl)-1,2,3,4- tetrahydroisoquinolin-6-yl)amino)- 5-(trifluoromethyl)pyrimidin-4-yl)- 4-methyl-3,4-dihydrothieno[2,3- f][1,4]thiazepin-5(2H)-one 1,1- dioxide::US20250144094, Example 246

SMILES CN1CCS(=O)(=O)c2cc(-c3nc(Nc4cc5c(cc4Cl)CN(CC4CC4)CC5)ncc3C(F)(F)F)sc2C1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 738014   

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738014(7-(2-((7-chloro-2- (cyclopropylmethyl)-1,2,3,4- te...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent