BDBM738156 Preparation of N-(5-(4-(4-acryloylpiperazin-1-yl)quinazolin-6-yl)-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide::US20250145589, Example 1

SMILES C=CC(=O)N1CCN(c2ncnc3ccc(-c4cnc(OC)c(NS(=O)(=O)c5ccc(F)cc5F)c4)cc23)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 738156   

LigandPNGBDBM738156(Preparation of N-(5-(4-(4-acryloylpiperazin-1-yl)q...)
Affinity DataIC50: 0.260nMAssay Description:The ADP-Glo™ kinase assay was used to assess the inhibition of PI3Kα with our compounds. The utilized proteins and assay reagents were obtained from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM738156(Preparation of N-(5-(4-(4-acryloylpiperazin-1-yl)q...)
Affinity DataIC50: 2.35nMAssay Description:The ADP-Glo™ kinase assay was used to assess the inhibition of PI3Kδ with our compounds. The utilized proteins and assay reagents were obtained from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent