BDBM738158 N-benzyl-2-(3-(pyridin-2-yl)-4-(quinolin-4-yl)-1H-pyrazol-1-yl)acetamide::US12297186, Example 1

SMILES O=C(Cn1cc(-c2ccnc3ccccc23)c(-c2ccccn2)n1)NCc1ccccc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 738158   

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandPNGBDBM738158(N-benzyl-2-(3-(pyridin-2-yl)-4-(quinolin-4-yl)-1H-...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandPNGBDBM738158(N-benzyl-2-(3-(pyridin-2-yl)-4-(quinolin-4-yl)-1H-...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent