BDBM738217 2-(3-(6-ethylpyridin-2-yl)-4-(quinolin-4-yl)-1H-pyrazol-1-yl)-N-(2-methylbenzyl)acetamide::US12297186, Example 19

SMILES CCc1cccc(-c2nn(CC(=O)NCc3ccccc3C)cc2-c2ccnc3ccccc23)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 738217   

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandPNGBDBM738217(2-(3-(6-ethylpyridin-2-yl)-4-(quinolin-4-yl)-1H-py...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandPNGBDBM738217(2-(3-(6-ethylpyridin-2-yl)-4-(quinolin-4-yl)-1H-py...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent