BDBM738218 N-(4-methylbenzyl)-2-(3-(6-methylpyridin-2-yl)-4-(quinolin-4-yl)-1H-pyrazol-1-yl)acetamide::US12297186, Example 20

SMILES Cc1ccc(CNC(=O)Cn2cc(-c3ccnc4ccccc34)c(-c3cccc(C)n3)n2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 738218   

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandPNGBDBM738218(N-(4-methylbenzyl)-2-(3-(6-methylpyridin-2-yl)-4-(...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandPNGBDBM738218(N-(4-methylbenzyl)-2-(3-(6-methylpyridin-2-yl)-4-(...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent