BDBM738241 Preparation of N-(5-(4-(4-acryloylpiperazin-1-yl)quinazolin-6-yl)-2-methoxypyridin-3-yl)-5-chlorothiophene-2-sulfonamide::US20250145589, Example 37

SMILES C=CC(=O)N1CCN(c2ncnc3ccc(-c4cnc(OC)c(NS(=O)(=O)c5ccc(Cl)s5)c4)cc23)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 738241   

LigandPNGBDBM738241(Preparation of N-(5-(4-(4-acryloylpiperazin-1-yl)q...)
Affinity DataIC50: 1.30nMAssay Description:The ADP-Glo™ kinase assay was used to assess the inhibition of PI3Kα with our compounds. The utilized proteins and assay reagents were obtained from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

LigandPNGBDBM738241(Preparation of N-(5-(4-(4-acryloylpiperazin-1-yl)q...)
Affinity DataIC50: 20.1nMAssay Description:The ADP-Glo™ kinase assay was used to assess the inhibition of PI3Kδ with our compounds. The utilized proteins and assay reagents were obtained from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent