BDBM738254 N-(5-(4-(2- acryloyl-2,7- diazaspiro[3.5] nonan-7- yl)quinazolin-6- yl)-2- methoxypyridin-3- yl)-2,6- difluorobenzene- sulfonamide::US20250145589, Example 50

SMILES C=CC(=O)N1CC2(CCN(c3ncnc4ccc(-c5cnc(OC)c(NS(=O)(=O)c6c(F)cccc6F)c5)cc34)CC2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 738254   

LigandPNGBDBM738254(N-(5-(4-(2- acryloyl-2,7- diazaspiro[3.5] nonan-7-...)
Affinity DataIC50: 0.610nMAssay Description:The ADP-Glo™ kinase assay was used to assess the inhibition of PI3Kα with our compounds. The utilized proteins and assay reagents were obtained from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM738254(N-(5-(4-(2- acryloyl-2,7- diazaspiro[3.5] nonan-7-...)
Affinity DataIC50: 11.4nMAssay Description:The ADP-Glo™ kinase assay was used to assess the inhibition of PI3Kδ with our compounds. The utilized proteins and assay reagents were obtained from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent