BDBM738259 N-(5-(4-(4-(1- acryloylazetidin- 3-yl)piperazin-1- yl)quinazolin-6- yl)-2- methoxypyridin-3- yl)-2,4- difluorobenzene- sulfonamide::US20250145589, Example 55

SMILES C=CC(=O)N1CC(N2CCN(c3ncnc4ccc(-c5cnc(OC)c(NS(=O)(=O)c6ccc(F)cc6F)c5)cc34)CC2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 738259   

LigandPNGBDBM738259(N-(5-(4-(4-(1- acryloylazetidin- 3-yl)piperazin-1-...)
Affinity DataIC50: 1.20nMAssay Description:The ADP-Glo™ kinase assay was used to assess the inhibition of PI3Kα with our compounds. The utilized proteins and assay reagents were obtained from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM738259(N-(5-(4-(4-(1- acryloylazetidin- 3-yl)piperazin-1-...)
Affinity DataIC50: 43.5nMAssay Description:The ADP-Glo™ kinase assay was used to assess the inhibition of PI3Kδ with our compounds. The utilized proteins and assay reagents were obtained from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent