BDBM738287 (E)-N-(2- chloro-5-(4-(2- (4-oxopent-2- enoyl)-2,6- diazaspiro [3.4]octan- 6-yl) quinazolin-6- yl)pyridin- 3-yl)-2,6- difluoro- benzene- sulfonamide::US20250145589, Example 86

SMILES CC(=O)/C=C/C(=O)N1CC2(CCN(c3ncnc4ccc(-c5cnc(Cl)c(NS(=O)(=O)c6c(F)cccc6F)c5)cc34)C2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 738287   

LigandPNGBDBM738287((E)-N-(2- chloro-5-(4-(2- (4-oxopent-2- enoyl)-2,6...)
Affinity DataIC50: 0.310nMAssay Description:The ADP-Glo™ kinase assay was used to assess the inhibition of PI3Kα with our compounds. The utilized proteins and assay reagents were obtained from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
TBA
Entry Details
US Patent