BDBM738297 Preparation of (E)-8-chloro-N-(2-methoxy-5-(4-(4-(4-oxopent-2-enoyl)piperazin-1-yl)quinazolin-6-yl)pyridin-3-yl)naphthalene-1-sulfonamide::US20250145589, Example 96

SMILES CCc1ncc(-c2ccc3ncnc(N4CCN(C(=O)/C=C/C(C)=O)CC4)c3c2)cc1NS(=O)(=O)c1cccc2cccc(Cl)c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 738297   

LigandPNGBDBM738297(Preparation of (E)-8-chloro-N-(2-methoxy-5-(4-(4-(...)
Affinity DataIC50: 1nMAssay Description:The ADP-Glo™ kinase assay was used to assess the inhibition of PI3Kα with our compounds. The utilized proteins and assay reagents were obtained from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM738297(Preparation of (E)-8-chloro-N-(2-methoxy-5-(4-(4-(...)
Affinity DataIC50: 171nMAssay Description:The ADP-Glo™ kinase assay was used to assess the inhibition of PI3Kδ with our compounds. The utilized proteins and assay reagents were obtained from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent