BDBM738336 Preparation of 2,4,6-trifluoro-N-(5-(4-(2-(2-fluoroacryloyl)-2,7-diazaspiro[3.5]nonan-7-yl) quinazoline-6-yl)-2-methoxypyridin-3-yl)benzenesulfonamide::US20250145589, Example 140

SMILES C=C(F)C(=O)N1CC2(CCN(c3ncnc4ccc(-c5cnc(OC)c(NS(=O)(=O)c6c(F)cc(F)cc6F)c5)cc34)CC2)C1

InChI Key

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 738336   

LigandPNGBDBM738336(Preparation of 2,4,6-trifluoro-N-(5-(4-(2-(2-fluor...)
Affinity DataIC50: 0.430nMAssay Description:The ADP-Glo™ kinase assay was used to assess the inhibition of PI3Kα with our compounds. The utilized proteins and assay reagents were obtained from ...More data for this Ligand-Target Pair
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US Patent