BDBM738338 (E)-2,4-difluoro- N-(2-methoxy- 5-(4-(6-(4- oxopent-2- enoyl)-3,6- diazabicyclo [3.1.1]heptan-3- yl)quinazolin-6- yl)pyridin-3-yl) benzene- sulfonamide::US20250145589, Example 142

SMILES COc1ncc(-c2ccc3ncnc(N4CC5CC(C4)N5C(=O)/C=C/C(C)=O)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 738338   

LigandPNGBDBM738338((E)-2,4-difluoro- N-(2-methoxy- 5-(4-(6-(4- oxopen...)
Affinity DataIC50: 0.570nMAssay Description:The ADP-Glo™ kinase assay was used to assess the inhibition of PI3Kα with our compounds. The utilized proteins and assay reagents were obtained from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent