BDBM738358 (E)-3,5- difluoro-N- (2-methoxy-5- (4-(2-(4- oxopent- 2-enoyl)-2,7- diazaspiro[3.5] nonan-7-yl) quinazolin-6- yl)pyridin-3- yl)pyridine-4- sulfonamide::US20250145589, Example 163

SMILES COc1ncc(-c2ccc3ncnc(N4CCC5(CC4)CN(C(=O)/C=C/C(C)=O)C5)c3c2)cc1NS(=O)(=O)c1c(F)cncc1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 738358   

LigandPNGBDBM738358((E)-3,5- difluoro-N- (2-methoxy-5- (4-(2-(4- oxope...)
Affinity DataIC50: 0.25nMAssay Description:The ADP-Glo™ kinase assay was used to assess the inhibition of PI3Kα with our compounds. The utilized proteins and assay reagents were obtained from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
TBA
Entry Details
US Patent