BDBM738377 (E)-2,4- difluoro-N-(2- (methylthio)- 5-(4-(4-(4- oxopent-2- enoyl) piperazin-1-yl) quinazolin-6- yl)pyridin-3- yl)benzene- sulfonamide::US20250145589, Example 182

SMILES CSc1ncc(-c2ccc3ncnc(N4CCN(C(=O)/C=C/C(C)=O)CC4)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 738377   

LigandPNGBDBM738377((E)-2,4- difluoro-N-(2- (methylthio)- 5-(4-(4-(4- ...)
Affinity DataIC50: 0.650nMAssay Description:The ADP-Glo™ kinase assay was used to assess the inhibition of PI3Kα with our compounds. The utilized proteins and assay reagents were obtained from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent