BDBM738404 Preparation of (E)-3-fluoro-4-(N-(2-methoxy-5-(4-(4-(4-oxopent-2-enoyl)piperazin-1-yl)quinazolin-4-yl)pyridin-3-yl)sulfamoyl)benzoic acid::US20250145589, Example 209

SMILES COc1ncc(-c2ccc3ncnc(N4CCN(C(=O)/C=C/C(C)=O)CC4)c3c2)cc1NS(=O)(=O)c1ccc(C(=O)O)cc1F

InChI Key

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 738404   

LigandPNGBDBM738404(Preparation of (E)-3-fluoro-4-(N-(2-methoxy-5-(4-(...)
Affinity DataIC50: 0.570nMAssay Description:The ADP-Glo™ kinase assay was used to assess the inhibition of PI3Kα with our compounds. The utilized proteins and assay reagents were obtained from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent