BDBM738727 Preparation of (R)-2-((1R,5S,6R)-3-(5-cyano-6-((S)-2-methylazetidine-1-yl)-4-(trifluoromethyl)pyridin-2-yl)-3-azabicyclo[3.1.0]hexan-6-yl)propionic acid and (S)-2-((1R,5S,6R)-3-(5-cyano-6-((S)-2-methylazetidine-1-yl)-4-(trifluoromethyl)pyridin-2-yl)-3-azabicyclo[3.1.0]hexan-6-yl)propionic acid::US20250145619, Example 19

SMILES C[C@H](C(=O)O)[C@@H]1[C@@H]2CN(c3cc(C(F)(F)F)c(C#N)c(N4CC[C@@H]4C)n3)C[C@@H]21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 738727   

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738727(Preparation of (R)-2-((1R,5S,6R)-3-(5-cyano-6-((S)...)
Affinity DataIC50: 24.7nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
TBA
Entry Details
US Patent