BDBM738731 Preparation of 2-((1R,5S,6R)-3-(5-cyano-6-((S)-2-methylazetidine-1-yl)-4-(trifluoromethyl)pyridin-2-yl)-3-azabicyclo[3.1.0]hexan-6-yl)acetic-2,2-d2 acid and 2-((1R,5S,6R)-3-(5-cyano-6-((S)-2-methylazetidine-1-yl)-4-(trifluoromethyl)pyridin-2-yl-3-d)-3-azabicyclo[3.1.0]hexan-6-yl)acetic-2,2-d2 acid::US20250145619, Example 23

SMILES [2H]c1c(N2C[C@@H]3[C@H](C2)[C@@H]3C([2H])([2H])C(=O)O)nc(N2CC[C@@H]2C)c(C#N)c1C(F)(F)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 738731   

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738731(Preparation of 2-((1R,5S,6R)-3-(5-cyano-6-((S)-2-m...)
Affinity DataIC50: 0.390nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
TBA
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US Patent