BDBM739787 (S)-1-(3-(4-amino-3-((6-chloro-1-cyclopropyl-1H-benzo[d]imidazol-5-yl)ethynyl)-7-propionyl-1H-pyrazolo[4,3-c]pyridin-1-yl)pyrrolidin-1-yl)prop-2-en-1-one::US20250152564, Example 45

SMILES C=CC(=O)N1CC[C@H](n2nc(C#Cc3cc4ncn(C5CC5)c4cc3Cl)c3c(N)ncc(C(=O)CC)c32)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 739787   

TargetFibroblast growth factor receptor 2 [V564F](Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM739787((S)-1-(3-(4-amino-3-((6-chloro-1-cyclopropyl-1H-be...)
Affinity DataIC50: 0.700nMAssay Description:TR-FRET (time-resolved fluorescence resonance energy transfer) method was used to detect the inhibitory activity of the compounds on FGFR1, FGFR2, FG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent