BDBM739794 US20250152719, Compound 27

SMILES CN1CCN([C@@H]2CCCN(c3cnc(C(N)=O)c(Nc4ccc(N5CCC(CN6CCc7ccc8c(C9CCC(=O)NC9=O)noc8c7CC6)CC5)cc4)n3)C2)C1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 739794   

TargetTyrosine-protein kinase BTK(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM739794(US20250152719, Compound 27)
Affinity DataIC50: 0.960nMAssay Description:The Assay Buffer was prepared, and the composition of the Assay Buffer was 50 mM Hepes (Gibco, 15630), 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, and 0.010% T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM739794(US20250152719, Compound 27)
Affinity DataIC50: 9nMAssay Description:The Assay Buffer was prepared, and the composition of the Assay Buffer was 50 mM Hepes (Gibco, 15630), 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, and 0.010% T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM739794(US20250152719, Compound 27)
Affinity DataIC50: 109nMAssay Description:The Assay Buffer was prepared, and the composition of the Assay Buffer was 50 mM Hepes (Gibco, 15630), 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, and 0.010% T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent