BDBM739796 US20250152719, Compound 50

SMILES CN1CCN([C@@H]2CCCN(c3cnc(C(N)=O)c(Nc4ccc(C5CCC6(CC5)CCN(CN5Cc7ccc8c(C9CCC(=O)NC9=O)noc8c7C5)CC6)cc4)n3)C2)C1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 739796   

TargetTyrosine-protein kinase BTK(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM739796(US20250152719, Compound 50)
Affinity DataIC50: 0.420nMAssay Description:The Assay Buffer was prepared, and the composition of the Assay Buffer was 50 mM Hepes (Gibco, 15630), 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, and 0.010% T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM739796(US20250152719, Compound 50)
Affinity DataIC50: 0.810nMAssay Description:The Assay Buffer was prepared, and the composition of the Assay Buffer was 50 mM Hepes (Gibco, 15630), 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, and 0.010% T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM739796(US20250152719, Compound 50)
Affinity DataIC50: 69nMAssay Description:The Assay Buffer was prepared, and the composition of the Assay Buffer was 50 mM Hepes (Gibco, 15630), 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, and 0.010% T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent