BDBM739813 3-methoxy-4-((4-((2''-methyl-3''-oxospiro[cyclopropane-1,1''-isoindolin]-4''-yl)oxy)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-N-(1-methylpiperidin-4-yl)benzamide ::US20250154134, Compound 3

SMILES COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc(C(F)(F)F)c(Oc2cccc3c2C(=O)N(C)C32CC2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 739813   

TargetFocal adhesion kinase 1(Human)
Wigen Biomedicine Technology (Shanghai)

US Patent
LigandPNGBDBM739813(3-methoxy-4-((4-((2'-methyl-3'-oxospiro[cyclopropa...)
Affinity DataIC50: 20nMAssay Description:A compound serially diluted with DMSO was mixed with a FAK recombinant protein. After the mixture was left to stand at room temperature for 10 min, a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent