BDBM740190 N-((1S)-2-((2- (bicyclo[1.1.1]pentan-1- ylcarbamoyl)-2-(6-oxo- 5,7- diazaspiro[2.5]octan-5- yl)-2,3-dihydro-1H- inden-5-yl)amino)-1- cyclohexyl-2-oxoethyl)- 1-methyl-1H-pyrazole- 5-carboxamide::US20250154138, Example 182

SMILES Cn1nccc1C(=O)N[C@H](C(=O)Nc1ccc2c(c1)CC(C(=O)NC13CC(C1)C3)(N1CC3(CC3)CNC1=O)C2)C1CCCCC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 740190   

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandPNGBDBM740190(N-((1S)-2-((2- (bicyclo[1.1.1]pentan-1- ylcarbamoy...)
Affinity DataIC50: 26.9nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent