BDBM740822 US12303509, Example 126

SMILES CN1C=Nc2ccc(c(c2C1=O)Cl)Nc3c(ccc(c3Cl)NS(=O)(=O)N4CC(C4)F)F

InChI Key InChIKey=SHENFUUACGRLOZ-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 740822   

LigandChemical structure of BindingDB Monomer ID 740822BDBM740822(US12303509, Example 126)
Affinity DataIC50: 3nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged “tracer” bound to B-Raf via TR-FRET from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)