BDBM740861 Preparation of (R)-2-amino-3-((6-(4,6-bis(((R)-1,1,1-trifluoropropan-2-yl)amino)-1,3,5-triazin-2-yl-pyridin-2-yl)thio)propanoic acid ::US12303512, Compound 5
SMILES C[C@@H](Nc1nc(N[C@H](C)C(F)(F)F)nc(-c2cccc(SC[C@H](N)C(=O)O)n2)n1)C(F)(F)F
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 740861
Affinity DataIC50: 1.00E+5nMAssay Description:A test compound is prepared as 10 mM stock in DMSO and diluted to 50× final concentration in DMSO, for a 50 μl reaction mixture. IDH enzyme activity ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:The primary reaction is performed in a volume of 50 μL 1× Buffer (150 mM NaCl, 20 mM Tris 7.5, 10 mM MgCl2, 0.05% (w/v) bovine serum albumin), contai...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:A test compound is prepared as 10 mM stock in DMSO and diluted to 50× final concentration in DMSO, for a 50 μl reaction mixture. IDH enzyme activity ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:The primary reaction is performed in a volume of 50 μL 1× Buffer (150 mM NaCl, 20 mM Tris 7.5, 10 mM MgCl2, 0.05% (w/v) bovine serum albumin), contai...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:A test compound is prepared as 10 mM stock in DMSO and diluted to 50× final concentration in DMSO, for a 50 μl reaction mixture. IDH enzyme activity ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:The primary reaction is performed in a volume of 50 μL 1× Buffer (150 mM NaCl, 20 mM Tris 7.5, 10 mM MgCl2, 0.05% (w/v) bovine serum albumin), contai...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:A test compound is prepared as 10 mM stock in DMSO and diluted to 50× final concentration in DMSO, for a 50 μl reaction mixture. IDH enzyme activity ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:The primary reaction is performed in a volume of 50 μL 1× Buffer (150 mM NaCl, 20 mM Tris 7.5, 10 mM MgCl2, 0.05% (w/v) bovine serum albumin), contai...More data for this Ligand-Target Pair