BDBM741360 US20250162989, Compound I-131

SMILES O=C(N[C@@H](Cc1ccccc1)C(=O)Nc1ccc(S(=O)(=O)NC2(CO)CC2)cc1)c1ccc(F)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 741360   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741360(US20250162989, Compound I-131)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741360(US20250162989, Compound I-131)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent