BDBM741620 N-hydroxy-4-(3-(4-((((1R,2S)-2-(1-phenyl-1H-pyrazol-4-yl)cyclopropyl)amino)methyl)piperidin-1-yl)propyl)benzamide::US20250162994, Example 3

SMILES O=C(NO)c1ccc(CCCN2CCC(CN[C@@H]3C[C@H]3c3cnn(-c4ccccc4)c3)CC2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 741620   

TargetLysine-specific histone demethylase 1A(Human)
Jubilant Epicore

US Patent
LigandPNGBDBM741620(N-hydroxy-4-(3-(4-((((1R,2S)-2-(1-phenyl-1H-pyrazo...)
Affinity DataIC50: 9nMAssay Description:LSD1 enzyme was produced in house. Tranylcypromine (TCP), LSD1 inhibitor was procured from Selleckchem. LSD1 enzyme, TCP and Biotinylated peptide sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Jubilant Epicore

US Patent
LigandPNGBDBM741620(N-hydroxy-4-(3-(4-((((1R,2S)-2-(1-phenyl-1H-pyrazo...)
Affinity DataIC50: 88nMAssay Description:Histone deacetylase assay was done as per manufacturer's instructions. Briefly, assay buffer, 200 uM HDAC substrate (fluorogenic HDAC acetylated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent