BDBM741717 US20250163056, Compound BPN-0026815

SMILES Cc1sc2c(c1C)C(=O)[C@]1(O)CCN(c3ccc(Cl)cc3)C1=N2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 741717   

TargetMyosin-2(Human)TBA
LigandPNGBDBM741717(US20250163056, Compound BPN-0026815)
Affinity DataKi:  270nMAssay Description:The skeletal muscle myosin II actin-activated ATPase assay is performed the same as for cardiac muscle myosin II with the following exceptions: Rabbi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMyosin-9(Human)TBA
LigandPNGBDBM741717(US20250163056, Compound BPN-0026815)
Affinity DataEC50:  800nMAssay Description:Cytokinesis is a cell-based assay to assess nonmuscle myosin II function, performed using COS7 cells. The assay is run in a 96 well plate, with 2,000...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM741717(US20250163056, Compound BPN-0026815)
Affinity DataKi:  2.80E+3nMAssay Description:The cardiac muscle myosin II actin-activated ATPase assay is a biochemical assay. Specifically, it is an NADH (nicotinamide adenine dinucleotide)-cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent