BDBM741819 US20250163056, Compound BPN-0028918

SMILES CCc1nc2cc(N3CC[C@@]4(O)C(=O)c5cc(C)c(C)cc5N=C34)ccc2s1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 741819   

TargetMyosin-2(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM741819(US20250163056, Compound BPN-0028918)
Affinity DataKi:  640nMAssay Description:The skeletal muscle myosin II actin-activated ATPase assay is performed the same as for cardiac muscle myosin II with the following exceptions: Rabbi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetMyosin-9(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM741819(US20250163056, Compound BPN-0028918)
Affinity DataEC50:  2.00E+3nMAssay Description:Cytokinesis is a cell-based assay to assess nonmuscle myosin II function, performed using COS7 cells. The assay is run in a 96 well plate, with 2,000...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetMyosin light chain kinase 2, skeletal/cardiac muscle(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM741819(US20250163056, Compound BPN-0028918)
Affinity DataKi:  1.10E+4nMAssay Description:The cardiac muscle myosin II actin-activated ATPase assay is a biochemical assay. Specifically, it is an NADH (nicotinamide adenine dinucleotide)-cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent