BDBM742425 1-[2-(4-cyclopropyl- sulfonylpiperazin-1- yl)propyl]-4-methyl- 5-[[2-[6-(2,2,2- trifluoroethyl) quinazolin-4-yl]-2,7- diazaspiro[3.5]nonan-7- yl]methyl]indole-2- carbonitrile::US20250163061, Compound 18

SMILES Cc1c(CN2CCC3(CC2)CN(c2ncnc4ccc(CC(F)(F)F)cc24)C3)ccc2c1cc(C#N)n2CC(C)N1CCNCC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 742425   

TargetMenin(Human)
Bala Therapeutics

US Patent
LigandPNGBDBM742425(1-[2-(4-cyclopropyl- sulfonylpiperazin-1- yl)propy...)
Affinity DataEC50: <75nMAssay Description:Compound activity was determined using recombinant MEN1 protein (Creativebiomart, Cat #MEN1-35H) and a custom fluorescein-labeled MLL4-43 peptide (Et...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent