BDBM742427 1-[(3,3-dioxo-1,3,4- oxathiazinan- 6-yl)methyl]- 4-methyl-5- [[2-[6-(2,2,2- trifluoroethyl) quinazolin-4-yl]-2,7- diazaspiro[3.5]nonan- 7-yl]methyl]indole-2- carbonitrile Example 40::US20250163061, Compound 21

SMILES Cc1c(CN2CCC3(CC2)CN(c2ncnc4ccc(CC(F)(F)F)cc24)C3)ccc2c1cc(C#N)n2CC1CNS(=O)(=O)CO1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 742427   

TargetMenin(Human)
Bala Therapeutics

US Patent
LigandPNGBDBM742427(1-[(3,3-dioxo-1,3,4- oxathiazinan- 6-yl)methyl]- 4...)
Affinity DataEC50: <75nMAssay Description:Compound activity was determined using recombinant MEN1 protein (Creativebiomart, Cat #MEN1-35H) and a custom fluorescein-labeled MLL4-43 peptide (Et...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent