BDBM742431 1-[(2R)-2-[(3S)-4- ethylsulfonyl-3-methyl- piperazin-1-yl]propyl]- 4-methyl-5-[[2-[6- (2,2,2-trifluoroethyl) quinazolin-4-yl]-2,7- diazaspiro[3.5]nonan-7- yl]methyl]indole-2- carbonitrile::US20250163061, Compound 25

SMILES CCS(=O)(=O)N1CCN([C@H](C)Cn2c(C#N)cc3c(C)c(CN4CCC5(CC4)CN(c4ncnc6ccc(CC(F)(F)F)cc46)C5)ccc32)C[C@@H]1C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 742431   

TargetMenin(Human)
Bala Therapeutics

US Patent
LigandPNGBDBM742431(1-[(2R)-2-[(3S)-4- ethylsulfonyl-3-methyl- piperaz...)
Affinity DataEC50: <75nMAssay Description:Compound activity was determined using recombinant MEN1 protein (Creativebiomart, Cat #MEN1-35H) and a custom fluorescein-labeled MLL4-43 peptide (Et...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent