BDBM742450 4-methyl-5-[[2-[2- (methylamino)- 6-(2,2,2- trifluoroethyl) quinazolin-4-yl]-2,7- diazaspiro[3.5]nonan- 7-yl]methyl]- 1-[[(2S)-5- oxomorpholin-2- yl]methyl]indole-2- carbonitrile::US20250163061, Compound 58

SMILES CNc1nc(N2CC3(CCN(Cc4ccc5c(cc(C#N)n5C[C@@H]5CNC(=O)CO5)c4C)CC3)C2)c2cc(CC(F)(F)F)ccc2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 742450   

TargetMenin(Human)
Bala Therapeutics

US Patent
LigandPNGBDBM742450(4-methyl-5-[[2-[2- (methylamino)- 6-(2,2,2- triflu...)
Affinity DataEC50: <75nMAssay Description:Compound activity was determined using recombinant MEN1 protein (Creativebiomart, Cat #MEN1-35H) and a custom fluorescein-labeled MLL4-43 peptide (Et...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent