BDBM744692 US20250171400, Compound 9AF

SMILES N[C@H]1C[C@H](C(=O)N2C[C@H](NC(=O)[C@@H]3C[C@H](F)CN3)C[C@@H]2C(=O)NCc2ccc(C#CC#CC3CC3)cc2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 744692   

TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
X-Biotix Therapeutics

US Patent
LigandPNGBDBM744692(US20250171400, Compound 9AF)
Affinity DataIC50: 75nMAssay Description:Dilutions of test compound were pre-incubated with 5 nM P. aeruginosa or E. coli LpxC for 10 minutes at room temperature in 50 mM NaH2PO4, 500 mM suc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent

TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli (strain K12))
X-Biotix Therapeutics

US Patent
LigandPNGBDBM744692(US20250171400, Compound 9AF)
Affinity DataIC50: 1.50E+3nMAssay Description:Dilutions of test compound were pre-incubated with 5 nM P. aeruginosa or E. coli LpxC for 10 minutes at room temperature in 50 mM NaH2PO4, 500 mM suc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent