BDBM744712 (2S)-1-(2R,4S)-4-([1,1''-biphenyl]-4-(4-ylmethyl) pyrrolidine-2-carbonyl)-N-(2-amino-6,7-dihydro-5H-cyclopenta[b]pyridin-5-yl) pyrrolidine-2-carboxamide ::US20250171414, Compound L028

SMILES Nc1ccc2c(n1)CCC2NC(=O)[C@@H]1CCCN1C(=O)[C@H]1C[C@H](Cc2ccc(-c3ccccc3)cc2)CN1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 744712   

TargetProthrombin(Human)TBA
LigandPNGBDBM744712((2S)-1-(2R,4S)-4-([1,1'-biphenyl]-4-(4-ylmethyl) p...)
Affinity DataIC50: 1.66E+4nMAssay Description:For thrombin assay, a fluorescent peptide substrate (Boc-VPR-AMC (R&D Systems)) was used and reacted in a buffer containing 20 mM Hepes (pH 7.4), 140...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent